Tiphanie Phillips Vogel, MD, PhD

Personal Statement

Dr. Vogel is a native of Southern California, where she played college basketball at Claremont McKenna College.  During her graduate studies in the Medical Scientist Training Program at the University of Chicago she worked on the development of CD8 T cell memory.  She subsequently completed a combined residency in internal medicine and pediatrics at Baylor College of Medicine.  Dr. Vogel temporarily left Houston to complete her fellowships in both pediatric and adult rheumatology at Washington University in St. Louis, where she was an instrumental part of the discovery of a new genetic cause of autoimmunity, STAT3 gain-of-function syndrome. Dr. Vogel returned to Baylor College of Medicine as faculty to help smooth the transition of pediatric rheumatology patients into adult rheumatology clinic and to continue to develop a basic science research program seeking to advance the understanding of and treatments for autoimmune diseases.  Dr. Vogel is passionate about the health of her patients!  She believes superior care results when the medical team works together with patients and their families to form individualized treatment plans based on cutting-edge medical knowledge and patient-focused goals.  Dr. Vogel lives in Houston with her husband, Dr. Adam Vogel (Pediatric Surgery), and their labrador retrievers.

Clinical  Interests:

Dr. Vogel has interest and expertise in all aspects of pediatric and adult autoimmune and immune dysregulatory conditions.  She has a special clinical interest in helping patients with childhood-onset rheumatologic conditions prepare for and make the transition into either her own or another adult rheumatology clinic. 

Research Interests:

Dr. Vogel’s laboratory focuses on several key missions:  determination of novel genetic causes of autoimmune and immune dysregulatory disorders, investigation of unique biomarkers and therapeutic targets in pediatric autoimmunity and advancement of the understanding of cytokine signals in health and in autoimmune disease.

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* Texas Children’s Hospital physicians’ licenses and credentials are reviewed prior to practicing at any of our facilities. Sections titled From the Doctor, Professional Organizations and Publications were provided by the physician’s office and were not verified by Texas Children’s Hospital.

Milner JD, Vogel TP, Forbes L, Ma CA, Stray-Pedersen A, Niemela JE, Lyons JJ, Engelhardt KR, Zhang Y, Topcagic N, Roberson EDO, Matthews H, Verbsky JW, Dasu T, Vargas-Hernandez A, Varghese N, McClain KL, Karam LB, Nahmod K, Makedonas G, Mace EM, Sorte HS, Perminow G, Rao VK, O’Connell MP, Price S, Su HC, Butrick M, McElwee J, Hughes J, Willet J, Swan D, Xu Y, Santibanez-Koref M, Slowik V, Dinwiddie DL, Ciaccio CE, Saunders CJ, Septer S, Kingsmore SF, White AJ, Cant AJ, Hambleton S, Cooper MA.  Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations.  Blood (2015) 125:  591.

Vogel TP, Milner JD, Cooper MA.  The ying and yang of STAT3 in human disease.  Journal of Clinical Immunology (2015) 35:  615.  

Weinreich MA, Vogel TP, Rao VK, Milner JD. Up, Down, All Around: Diagnosis and treatment of a novel STAT3 variant. Frontiers in Pediatrics (2017) 5:  49.

Fabre A, Marchal S, Forbes LR, Vogel TP, Barlogis V, Triolo V, Rohrlich P-S, Etienne B, Frankel D, Ambrosetti D, Hoflack M, Baque M, Bosdure E, Baravalle M, Carsin A, Dubus J-C, Giovannini-Chami L.  STAT3 GOF: a new kid on the block in interstitial lung diseases. American Journal of Respiratory and Critical Care Medicine (2018) 197:e22.

Forbes LR, Vogel TP, Cooper MA, Castro-Wagner J, Schussler E, Weinacht KG, Plant A, Su HC, Allenspach EJ, Slatter M, Abinun M, Lilic D, Cunningham-Rundles C, Eckstein O, Olbrich, P, Guillerman RP, Patel NC, Demirdag YY, Zerbe C, Freeman AF, Holland SM, Szabolcs P, Gennery A, Torgerson TR, Milner JD, Leiding JW.  Jakinibs for the treatment of immunodysregulation in patient with gain of function STAT1or STAT3mutations. Journal of Allergy and Clinical Immunology (2018), doi: 10.1016/j.jaci.2018.07.020.

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https://www.ncbi.nlm.nih.gov/sites/myncbi/12Mux_u0f1lQs/bibliography/47…